LoPressure Design

Information Capture

Mon, 28 Jun 2010 05:30:21 +0000

Web Project

Thank you for taking the time to complete this Proposal Planner.

Skip over any questions that you feel are irrelevant.

Once completed please email a copy back to me: moc.erusserpol@notron

Basic Information

Organisation, domain name, contacts, schedule, budget

What is the name of your organisation? What is the domain name you are using/intend to use? Briefly describe your organisation and the service/product your site will offer. Who are the main contacts for this project?
Names, phone numbers and email addresses. When do you expect this project to start and when does it need to be completed? Are there specific reasons for these dates?
e.g. Tradeshows, product launch, budget deadlines. What is the budget for this project?
Your budget dictates how much time we can devote to your website.

Objectives

Business, success

What are the main reasons for creating a new, or updating an old, website?
Please list the business objectives in order of importance.
e.g. Improve sales, increase customer satisfaction, reduce time spent looking for information. How do you intend to measure that the site is a success?
e.g. 20% increase in sales, 70% of surveyed users expressing satisfaction, 30% reduction in time spent looking for information.

Current Site (if applicable)

What works, what doesn't, problems?

What aspects of your current site work well and why do you think they are successful? What aspects of your current site are unsuccessful and why do you think that is? What problems have your visitors/customers reported? How do you currently update your site? Are you happy with this process?
e.g. Content Management System, raw edits to HTML.

Your Visitors

Current market demographics

Please describe the demographic of the visitors to your site. Do you want to change/expand this? If so, please describe.
e.g. Men seeking auto parts, women seeking jewellery.

Design and Content

Perceptions, competitors, colours, styles, functions, features

Please describe how you would like visitors to perceive the (re)designed site.
e.g. modern, professional, friendly, fun etc. Please list any of your competitors' websites. Are there elements of these sites that you would like to use? If so, please list them. List the websites (related or not) that have a visual design that is appealing to you. Please explain why.
e.g. colour scheme, layout, functions and features used. Outline any ideas and/or features you would like to see implemented on your site. How would these features support your business goals?
e.g. provide recommendations to help users find related items and promote up-selling (cross-selling.)

Additional Comments

Please let us know about any other information that we would find helpful.

This is the place for you to add any additional information that did not fit into the above questions.

Myoglobin

Mon, 31 May 2010 15:03:59 +0000

Myoglobin, protein molecule isolated from the cells of vertebrate skeletal muscle that is both a structural and functional relative of hemoglobin , the oxygen-transport protein of the blood of higher animals. Myoglobin, which is composed of a single polypeptide chain of 153 amino acid residues, has the ability to store oxygen by binding it to an iron atom; iron is part of myoglobin's essential chemical composition. The complete amino acid sequence of myoglobin has been determined; it is a relatively small protein with a molecular weight of approximately 17,000 grams per mole. The distribution of myoglobin among the higher animals is a reflection of its physiological function.

It is found abundantly in the tissues of diving mammals, e.g., the whale, the seal, and the dolphin. High concentrations of myoglobin in these animals presumably allows them to store sufficient oxygen to remain underwater for long periods. Myoglobin is found abundantly in man only in cardiac muscle, which, by virtue of its essential function, must possess the capacity for continued activity when environmental oxygen concentrations are low. Myoglobin has been investigated intensely and is the first protein molecule to have been completely described in terms of its three-dimensional geometry. This achievement won the British scientist John Kendrew a share in the 1962 Nobel Prize for Chemistry.
The Columbia Encyclopedia, Sixth Edition | 2008

Myoglobin and haemoglobin are haemeproteins whose physiological importance is principally related to their ability to bind molecular oxygen. Myoglobin is a monomeric haeme protein found mainly in muscle tissue where it serves as an intracellular storage site for oxygen. During periods of oxygen deprivation oxymyoglobin releases its bound oxygen which is then used for metabolic purposes.

The tertiary structure of myoglobin is that of a typical water soluble globular protein. Its secondary structure is unusual in that it contains a very high proportion (75%) of α-helical secondary structure. A myoglobin polypeptide is comprised of 8 separate right handed α-helices, designated A through H, that are connected by short non helical regions. Amino acid R-groups packed into the interior of the molecule are predominantly hydrophobic in character while those exposed on the surface of the molecule are generally hydrophilic, thus making the molecule relatively water soluble.

Structure of Myoglobin with haeme

Each myoglobin molecule contains one haeme prosthetic group inserted into a hydrophobic cleft in the protein. Each haeme residue contains one central coordinately bound iron atom that is normally in the Fe2+, or ferrous, oxidation state. The oxygen carried by haemeproteins is bound directly to the ferrous iron atom of the haeme prosthetic group. Oxidation of the iron to the Fe3+, ferric, oxidation state renders the molecule incapable of normal oxygen binding.

Hydrophobic interactions between the tetrapyrrole ring and hydrophobic amino acid R groups on the interior of the cleft in the protein strongly stabilize the haeme protein conjugate. In addition a nitrogen atom from a histidine R group located above the plane of the haeme ring is coordinated with the iron atom further stabilizing the interaction between the haeme and the protein. In oxymyoglobin the remaining bonding site on the iron atom (the 6th coordinate position) is occupied by the oxygen, whose binding is stabilized by a second histidine residue.

Carbon monoxide also binds coordinately to haeme iron atoms in a manner similar to that of oxygen, but the binding of carbon monoxide to haeme is much stronger than that of oxygen. The preferential binding of carbon monoxide to haeme iron is largely responsible for the asphyxiation that results from carbon monoxide poisoning.

Terms and Conditions

Mon, 31 May 2010 12:18:13 +0000

Privacy

Mon, 31 May 2010 11:52:33 +0000

Cookies

LoPressure Design (lopressure.com) uses cookies to store session information so you will not see the same advertisement repeatedly.

External Site Links

LoPressure Design (lopressure.com) links to other websites on the internet. Content and Privacy Policies are the responsibility of their respective owners.

Advertisers

Most advertisements on LoPressure Design (lopressure.com) are provided by outside advertisement companies and may contain cookies. These cookies are collected by their respective companies and are not accessible to LoPressure Design (lopressure.com).

IP Addresses and Logging

LoPressure Design (lopressure.com) server logs information about visitors, including IP addresses, date/time visited, referring website, length of stay, etc. This information is used for site statistics only.

Customer Information & Credit Card Transactions

Limited information is supplied to LoPressure Design (lopressure.com) in the event of a sale. This includes your name, IP Address and website domain name. This information is not sold or distributed to third parties. Credit card payments are processed through PayPal.com. This information is collected solely for PayPal to securely process the order, and is not accessible to LoPressure Design (lopressure.com).

All questions and concerns should be directed here: moc.erusserpol@notron

Sliding Panels

Mon, 19 Apr 2010 13:23:56 +0000

We provide turn-key, high-quality
solutions regardless of the project size.

We are a professional, full-service web development company that creates elegant, efficient, effective website designs and web applications.

Services

Website design / build Full design, development & build of your custom website. Converting designs to XHTML & CSS We convert your designs into website-ready W3C-valid XHTML & CSS Wordpress themes Customisation & conversion of Wordpress themes. Wordpress-as-a-CMS Manage your site's content & look yourself. Accessibility consultancy Increase your audience reach & show your social responsibility by making your websites more accessible.

A little background ...

LoPressure Design was set up in August 2009 by Norton Miller. Our vision is to help small business owners get their company noticed in today's busy market. Using years of web development experience, an innovative pricing/cost structure and a fresh technical and creative approach we offer a service that is comparable to the top design agencies. We believe our design solutions are cost-effective and are affordable the small business owner.

We provide top-quality solutions at budget-friendly prices.

Next Prev

Consultation and Planning

An effective website requires a clear definition of goals, comprehensive planning, and expert execution. For sites that have not yet been built, or for those that are ready to undergo a transformation, we can provide information on the architecture, planning, development and implementation of effective design. Contact us for a free consultation.

Architecture and Design

Regardless of the project size we offer robust and sophisticated "out-of-the-box" or custom-built solutions. From a typical Content Management System (CMS) to specifically targeted web applications we produce highly usable, modular and search-engine optimized solutions. Talk to us if you'd like to know more about architecture, design, planning & development.

Project Support

We aim to establish long-term relationships with our clients. It's important to us to support you beyond the initial launch of your website through retainers and hourly support.

Portfolio

Fri, 11 Dec 2009 15:27:36 +0000